Pathogen and Microbiome Division
TGen North, located in Flagstaff, Arizona, is the home of TGen's Pathogen and Microbiome Division. Led by Dr. David Engelthaler and Dr. Paul Keim, TGen North focuses on diagnostic, analytic, forensic, ecologic and epidemiologic research of microbes important to medicine, public health and biodefense. From global risks like tuberculosis to local threats like Valley Fever, and from understanding the human microbiome to the human immune system, we have developed the capability - therefore we have the responsibility to make positive impacts on human health.

TGen North is a proud contributor to the vibrant Flagstaff research community, actively participates in local education and outreach activities, and we are a founding member of STEM City, resulting in Flagstaff being named America’s First STEM Community.

TGen North News

TED Talks - Dave Engelthaler

TED Talks - Dave Engelthaler

Connect the first world to the third world - As a genomic epidemiologist, Dave Engelt...

TGen Talks


TGen North advances public health, clinical medicine and biodefense through targeted and global microbial genomics. Our faculty and staff value the opportunity to share our research with the great Flagstaff community through laboratory tours. To learn more, or sign up for a tour, please click here.


We apply advanced laboratory and computer technology to explore the human microbiome, the next frontier in our understanding of the relationship of microbes to human health and disease.


We view the larger health problems of our time through a comprehensive approach to humans, animals and the environment, through the application of next generation technology and knowledge.

Healthcare Acquired Infections

We partner with health-care providers to characterize and track critical pathogens in hospitals and clinics, with a focus on the continual advancement of antibiotic resistance, allowing physicians to provide personalized therapy and prevent outbreaks.


Through sequencing technology, we are finding more accurate diagnoses and treatments for this pathogen that affects one-third of the world population.


From strep to influenza to rare fungal infections, we have developed advanced capabilities to assist public health and healthcare officials investigating disease outbreaks in our backyard and around the world.


TGen North and Northern Arizona University work to support America’s biosecurity and protection from pathogens such as anthrax and plague, by collaborating with law enforcement, public health, military and intelligence communities.

Arizona COVID-19 Sequencing Dashboard

A quick and easy way to view data from sequencing conducted by TGen North, Arizona State Public Health Laboratory, CDC, ASU, UArizona, U.S. Airforce and Quest Diagnostics.

TGen North Clinical Laboratory

TGen North Clinical Laboratory (TNCL) is a CLIA-certified, high complexity clinical laboratory located in Flagstaff, Arizona. Our clinical laboratory offers PCR and serology testing for COVID-19.


Paul Keim
Distinguished Professor and Co-Director
Pathogen and Microbiome Division
Sarah K. Highlander
Research Professor
Pathogen and Microbiome Division
David Engelthaler
Associate Professor and Co-Director
Pathogen and Microbiome Division
John Altin
Assistant Professor
Pathogen and Microbiome Division
Jolene Bowers
Research Assistant Professor
Pathogen and Microbiome Division