Keehoon Lee

Keehoon Lee Ph.D.

Research Assistant Professor
Pathogen and Microbiome Division

Co-Director of the TGen Integrated Microbiomics Center

Keehoon Lee Ph.D.

Dr. Lee has a broad background in microbiology, genetics, and immunology with specific expertise in biofilms and respiratory microbiome analyses. His Ph.D. studies in the Department of Microbiology and Immunology at Yonsei University in South Korea were focused on characterizing genetics and molecular determinants of Pseudomonas aeruginosa mono- and dual-species biofilms. During his postdoctoral work at the University of Northern Arizona, Dr. Lee investigated the effects of microbial communities on chronic respiratory disease in the upper and lower respiratory tracts. Specifically, the focus of this investigation was to characterize the relationships between the disease and bacterial-fungal interactions. Dr. Lee is currently working at TGen North as a research assistant professor and a co-director of the TGen Integrated Microbiomics Center, where we conduct various types of microbiome analyses and explore clinical implications of the microbiome.

Predicting Neurodegenerative Disease Using Prepathology Gut Microbiota Composition: a Longitudinal Study in Mice Modeling Alzheimer’s Disease Pathologies. Borsom EM, ..., Lee K, Caporaso JG, Cope EK. Microbiology Spectrum, March/April 2023, 11(12):e03458-22.

Influence of fecal microbiota transplantation on gut microbiota composition in transgenic mice modeling amyloid-β plaques and neurofibrillary tangles. Borsom EM, ..., Lee K, Caporaso JG, Cope EK. Alzheimer's & Dementia, Dec 2022, 18(Suppl. 5):e066307.

IL-13–programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function. Kotas ME, ..., Lee K, ..., Gordon ED. JCI Insight, 7(13):e159832.

Co-infection of Malassezia sympodialis With Bacterial Pathobionts Pseudomonas aeruginosa or Staphylococcus aureus Leads to Distinct Sinonasal Inflammatory Responses in a Murine Acute Sinusitis ModelLee K, Zhang I, Kyman S. Kask O, Cope EK. Frontiers in Cellular and Infection Microbiology, Sep 2020, 10:472.

Molecular determinants for the thickened matrix in a dual-species Pseudomonas aeruginosa and Enterococcus faecalis biofilmLee K, Lee KM, Kim D, Yoon SS. Applied and Environmental Microbiology, Oct 2017, 83(21). 

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