Nicholas Schork

Nicholas Schork Ph.D.

Distinguished Professor and Director
Quantitative Medicine & Systems Biology Division

Nicholas Schork Ph.D.

Nicholas J. Schork is a Distinguished Professor and Director of the Quantitative Medicine and Systems Biology Division at TGen. In addition, he is a Professor and Director of Human Biology at the J. Craig Venter Institute (JCVI), and an adjunct Professor of Psychiatry and Family and Preventive Medicine in the Division of Biostatistics at the University of California, San Diego (UCSD). 

Schork’s interests and expertise are in quantitative translational biomedical science and integrated approaches to complex biological and medical problems, especially the design and implementation of studies to dissect the determinants of complex traits and diseases. He has published over 500 scientific articles and book chapters on the analysis of complex, multifactorial traits and diseases, including clinical trials methodology. A member of several scientific journal editorial boards, Dr. Schork is a frequent participant in U.S. National Institutes of Health-related steering committees and review boards, has mentored over 50 graduate students and postdoctoral fellows, and has founded or served on the advisory boards of ten companies. In addition, he is currently director of the quantitative components of a number of national research consortia, including the NIA-sponsored Longevity Consortium. Dr. Schork earned a B.A. in Philosophy, M.A. in Philosophy, M.A. in Statistics, and Ph.D. in Epidemiology, all from the University of Michigan in Ann Arbor.

Prior to joining JCVI, Dr. Schork was from 2007-2013, a Professor in Molecular and Experimental Medicine at The Scripps Research Institute, Director of Biostatistics and Bioinformatics at the Scripps Translational Science Institute, and Director of Research at Scripps Genomic Medicine, a division of Scripps Health. From 2001-2007, Dr. Schork was a Professor of Biostatistics and Psychiatry, and Co-Director of the Center for Human Genetics and Genomics at UCSD. From 1994-2000, he was an Associate Professor of Epidemiology and Biostatistics at Case Western Reserve University in Cleveland, Ohio, and an Adjunct Associate Professor of Biostatistics at Harvard University. During 1999 and 2000, Dr. Schork took a sponsored leave of absence from CWRU to conduct research as the Vice President of Statistical Genomics at the French biotechnology company, Genset, where he helped guide efforts to construct the first high-density map of the human genome.


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Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond. Schork NJ, Nazor K. Adv Genet. 2017;97:81-113. Epub 2017 Jul 25. 

Single-Subject Studies in Translational Nutrition Research. Schork NJ, Goetz LH. Annu Rev Nutr. 2017 Aug 21;37:395-422. Epub 2017 Jul 17. 

Personalized medicine: Time for one-person trials. Schork NJ. Nature. 2015 Apr 30;520(7549):609-11. No abstract available. 

Clinical implications of human population differences in genome-wide rates of functional genotypes. Torkamani A, Pham P, Libiger O, Bansal V, Zhang G, Scott-Van Zeeland AA, Tewhey R, Topol EJ, Schork NJFrontiers in Genetics. 2012, Jan 01; 3: 211.

The importance of phase information for human genomics. Tewhey R, Bansal V, Torkamani A, Topol EJ, Schork NJ. Nature Reviews. Genetics. 2011, Mar 01; 12: 215-23.

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