Nicholas Schork

Nicholas Schork Ph.D.

Distinguished Professor and Director
Quantitative Medicine & Systems Biology Division

Nicholas Schork Ph.D.

Nicholas J. Schork is Deputy Director and Distinguished Professor of Quantitative Medicine at The Translational Genomics Research Institute (TGen) in Phoenix, AZ. Dr. Schork is also Adjunct Professor of Population Sciences as well as Molecular and Cellular Biology at City of Hope, Adjunct Professor of Psychiatry and Biostatistics at the University of California, San Diego and Adjunct Professor of Integrative Structural and Computational Biology at Scripps Research.

Prior to his current positions, Dr. Schork was Professor and Director of Human Biology at the J. Craig Venter Institute and previously Professor, Molecular and Experimental Medicine, at The Scripps Research Institute (TSRI) and Director of Bioinformatics and Biostatistics for the Scripps Translational Science Institute (STSI). Dr. Schork has also held faculty appointments at Case Western Reserve University (CWRU) and Harvard University. Between 1999 and 2000 Dr. Schork took a leave of absence from CWRU to conduct research as Vice President of Statistical Genomics at the French Biotechnology company, Genset, where he helped guide efforts to construct the first high-density map of genetic variation in the human genome.

Dr. Schork has published over 550 articles in many areas of biomedical and translation science, including articles detailing novel methodologies and applications leveraging integrated approaches to disease diagnosis, treatment, and prevention as well as clinical trials design. He also has a long history of collaborative and consortium-related research in which he has contributed analysis methodology and applied data analysis expertise. For example, Dr. Schork is the scientific director of the current NIA-funded Longevity Consortium, whose goals are to identify and characterize factors that contribute to human longevity. Dr. Schork has 9 patents associated with genetic analysis methodology, been involved with more than 10 start-up companies, and has mentored over 75 students and post-doctoral fellows.


Artificial intelligence and machine learning in clinical development: a translational perspective    Shah P, Kendall F, Khozin S, Goosen R, Hu J, Laramie J, Ringel M, Schork N., NPJ Digit Med. 2019 Jul 26;2:69. doi: 10.1038/s41746-019-0148-3. eCollection 2019. PMID: 31372505

Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond.   Schork NJ, Nazor K., Adv Genet. 2017;97:81-113. Epub 2017 Jul 25.

Single-Subject Studies in Translational Nutrition Research.    Schork NJ, Goetz LH. Annu Rev Nutr. 2017 Aug 21;37:395-422. Epub 2017 Jul 17.

Personalized medicine: Time for one-person trials.  Schork NJ. Nature. 2015 Apr 30;520(7549):609-11. No abstract available.

The importance of phase information for human genomics.    Tewhey R, Bansal V, Torkamani A, Topol EJ, Schork NJ. Nature Reviews. Genetics. 2011, Mar 01; 12: 215-23.

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