Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells. Altin JA, Daley SR, Howitt J, Rickards HJ, Batkin AK, Horikawa K, Prasad SJ, Nelms KA, Kumar S, Wu LC, Tan SS, Cook MC, Goodnow CC. Proc Natl Acad Sci U S A. 2014, 111(6):2067-74.
ZBTB7B (Th-POK) Regulates the Development of IL-17-Producing CD1d-Restricted Mouse NKT Cells. Enders A, Stankovic S, Teh C, Uldrich AP, Yabas M, Juelich T, Altin JA, Frankenreiter S, Bergmann H, Roots CM, Kyparissoudis K, Goodnow CC, Godfrey DI. J Immunol. 2012, 189:5240-9.
IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2- dependent manner from Th2 effectors during chronic inflammation. Altin JA, Goodnow CC, Cook MC. J Immunol. 2012, 88:5478-88.
Foxp3+ regulatory T cells exert asymmetric control over helper responses by inducing Th2 cell apoptosis. Tian L, Altin JA, Makaroff LM, Cook MC, Goodnow CC, Dooley J, Liston A. (2011) Blood. 118(7): 1845-53.
Visualizing the role of Cbl-b in control of islet-reactive CD4 T cells and susceptibility to type 1 diabetes. Hoyne GF, Flening E, Yabas M, Teh C, Altin JA, Randall K, Thien CB, Langdon WY, Goodnow CC. (2011) J Immune. 186(4):2024-32.
Decreased T-cell receptor signaling through CARD11 differentially compromises forkhead box protein 3-positive regulatory versus T(H)2 effector cells to cause allergy. Altin JA, Tian L, Liston A, Bertram EM, Goodnow CC, Cook MC. (2011). J Allergy Clin Immunol. 127(5):1277-85.
Understanding the genetic regulation of IgE production. Altin JA, Shen C, Liston A. (2010) Blood Rev. 24:163-9.