Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression. Mylan R Blomquist, Shannon Fortin Ensign, Fulvio D'Angelo, Joanna J Phillips, Michele Ceccarelli, Sen Peng, Rebecca F Halperin, Francesca P Caruso, Luciano Garofano, Sara A Byron, Winnie S Liang, David W Craig, John D Carpten, Michael D Prados, Jeffrey M Trent, Michael E Berens, Antonio Iavarone, Harshil Dhruv, Nhan L Tran. Neurooncol Adv. 2020 Jun 19;2(1):vdaa078. eCollection Jan-Dec 2020.
Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer. Olena M Vaske, Isabel Bjork, Sofie R Salama, Holly Beale, Avanthi Tayi Shah , Lauren Sanders, Jacob Pfeil, Du L Lam, Katrina Learned, Ann Durbin, Ellen T Kephart, Rob Currie, Yulia Newton, Teresa Swatloski, Duncan McColl, John Vivian, Jingchun Zhu, Alex G Lee, Stanley G Leung, Aviv Spillinger, Heng-Yi Liu, Winnie S Liang, Sara A Byron, Michael E Berens, Adam C Resnick, Norman Lacayo, Sheri L Spunt, Arun Rangaswami, Van Huynh, Lilibeth Torno, Ashley Plant, Ivan Kirov, Keri B Zabokrtsky, S Rod Rassekh, Rebecca J Deyell, Janessa Laskin, Marco A Marra, Leonard S Sender, Sabine Mueller, E Alejandro Sweet-Cordero, Theodore C Goldstein, David Haussler. JAMA Netw Open. 2019 Oct 2;2(10):e1913968.
Genomics-Enabled Precision Medicine for Cancer. Alison Roos, Sara A Byron. Cancer Treat Res. 2019;178:137-169.
Leveraging Spatial Variation in Tumor Purity for Improved Somatic Variant Calling of Archival Tumor Only Samples. Rebecca F Halperin, Winnie S Liang, Sidharth Kulkarni, Erica E Tassone, Jonathan Adkins, Daniel Enriquez, Nhan L Tran, Nicole C Hank, James Newell, Chinnappa Kodira, Ronald Korn, Michael E Berens, Seungchan Kim, Sara A Byron. Front Oncol. 2019 Mar 20;9:119. eCollection 2019.
A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium. Sabine Mueller, Payal Jain, Winnie S Liang, Lindsay Kilburn, Cassie Kline, Nalin Gupta, Eshini Panditharatna, Suresh N Magge, Bo Zhang, Yuankun Zhu, John R Crawford, Anu Banerjee, Kellie Nazemi, Roger J Packer, Claudia K Petritsch, Nathalene Truffaux, Alison Roos, Sara Nasser, Joanna J Phillips, David Solomon, Annette Molinaro, Angela J Waanders, Sara A Byron, Michael E Berens, John Kuhn, Javad Nazarian, Michael Prados, Adam C Resnick. Int J Cancer. 2019 Oct 1;145(7):1889-1901. pub 2019 Apr 3.
Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma. Sara A Byron, Nhan L Tran, Rebecca F Halperin, Joanna J Phillips, John G Kuhn, John F de Groot, Howard Colman, Keith L Ligon, Patrick Y Wen, Timothy F Cloughesy, Ingo K Mellinghoff, Nicholas A Butowski, Jennie W Taylor, Jennifer L Clarke, Susan M Chang, Mitchel S Berger, Annette M Molinaro, Gerald M Maggiora, Sen Peng, Sara Nasser, Winnie S Liang, Jeffrey M Trent, Michael E Berens, John D Carpten, David W Craig, Michael D Prados. Clin Cancer Res. 2018 Jan 15;24(2):295-305. Epub 2017 Oct 26.
FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study. Yvette W Jeske, Shamshad Ali, Sara A Byron, Feng Gao, Robert S Mannel, Rahel G Ghebre, Paul A DiSilvestro, Shashikant B Lele, Michael L Pearl, Amy P Schmidt, Heather A Lankes, Nilsa C Ramirez, Golnar Rasty, Matthew Powell, Paul J Goodfellow, Pamela M Pollock. Gynecol Oncol. 2017 May;145(2):366-373. Epub 2017 Mar 15.
Translating RNA sequencing into clinical diagnostics: opportunities and challenges. Sara A Byron, Kendall R Van Keuren-Jensen, David M Engelthaler, John D Carpten, David W Craig. Nat Rev Genet. 2016 May;17(5):257-71. Epub 2016 Mar 21.
Toward precision medicine in glioblastoma: the promise and the challenges. Michael D Prados, Sara A Byron, Nhan L Tran, Joanna J Phillips, Annette M Molinaro, Keith L Ligon, Patrick Y Wen, John G Kuhn, Ingo K Mellinghoff, John F de Groot, Howard Colman, Timothy F Cloughesy, Susan M Chang, Timothy C Ryken, Waibhav D Tembe, Jeffrey A Kiefer, Michael E Berens, David W Craig, John D Carpten, Jeffrey M Trent. Neuro Oncol. 2015 Aug;17(8):1051-63. Epub 2015 May 1.
An integrated framework for reporting clinically relevant biomarkers from paired tumor/normal genomic and transcriptomic sequencing data in support of clinical trials in personalized medicine. Sara Nasser, Ahmet A Kurdolgu, Tyler Izatt, Jessica Aldrich, Megan L Russell, Alexis Christoforides, Wiabhav Tembe, Jeffery A Keifer, Jason J Corneveaux, Sara A Byron, Karen M Forman, Clarice Zuccaro, Jonathan J Keats, Patricia M Lorusso, John D Carpten, Jeffrey M Trent, David W Craig. Pac Symp Biocomput. 2015;56-67.
