Technology expected to enhance speed and quality of
research
RainDance Technologies Inc. today announced the shipment of an RDT
1000 and Sequence Enrichment Solution to the Translational Genomics
Research Institute (TGen).
RainDance, based in Lexington, Mass., is a provider of innovative
microdroplet-based solutions for human health and disease
research.
TGen, a non-profit biomedical research institute based in Phoenix,
Arizona, focuses on the translation of laboratory discoveries into
personalized medicine, developing earlier diagnostics and better
treatments for patients with many forms of cancer, neurological and
cardiovascular diseases, and infectious diseases.
Dr. David Duggan, an Investigator in TGen's Genetic Basis of Human
Disease Division, said one of the initial applications of the
RainDance solution would focus on resequencing regions of the human
genome identified as part of genome-wide association studies.
"The RainDance technology has tremendous breadth. We are also
discussing its use in candidate gene and pathways studies, as well
as targeting known disease-causing genes," Dr. Duggan said.
Dr. Jeffrey Trent, TGen's President and Research Director, said
the use of RainDance products should further improve the speed and
quality of TGen's cutting-edge scientific investigations.
"TGen should significantly reduce the time required to conduct
experiments by exponentially accelerating multiple applications for
genome-level partitioning, including the generation of large
amounts of targeted resequencing data," Dr. Trent said.
"TGen is a recognized leader in the application of next-generation
sequencing technologies to translational medicine research," said
Christopher McNary, President and Chief Executive Officer of
RainDance Technologies. "Our Sequence Enrichment Solution and RDT
1000 system will accelerate their ability to perform large-scale
targeted resequencing studies that will help realize the exciting
benefits of personalized medicine."
The RainDance solution consists of the RDT 1000 instrument,
consumables kits, and custom PCR primer libraries. The solution
uses RainDance's breakthrough RainStorm™ microdroplet-based
technology platform.
The simplicity and speed of the technology are designed to
maximize the efficiency of next-generation DNA sequencing
workflows. The RDT 1000 generates picoliter-volume PCR reactions at
the rate of 10 million discrete reactions per hour. High-speed
sample processing is further enhanced by the fact that the Sequence
Enrichment Solution uses a library of PCR primers in droplets
enabling the amplification of hundreds to thousands of genomic loci
in a single tube. The technology leverages the specificity of PCR
to provide high breadth of coverage for the regions of
interest.
The RainStorm format avoids the limitations of traditional
multiplex hybridization and amplification technologies. RainDance's
solution minimizes process-induced bias or error and requires only
a few micrograms of genomic DNA.
The commercial version of the Sequence Enrichment Solution is now
being shipped in North America and will soon be delivered to the
company's first customer in Europe. For more information, contact
[email protected], call 781-861-6300, or visit the company's
Website at www.raindancetech.com.
About RainDance Technologies, Inc.
RainDance Technologies, Inc., is a provider of innovative
microdroplet-based solutions for human health and disease research.
The speed and simplicity of the company's exciting new technology
platform enable researchers to design experiments in ways that were
previously unaffordable or unimaginable. The company's RainStorm™
technology produces picoliter-volume droplets at a rate of 10
million per hour. Each droplet is the functional equivalent of an
individual test tube and can contain a single molecule, reaction,
or cell. This versatile technology can adapt proven assays for
high-speed workflows with minimized process-induced bias or
error.
RainDance's initial application will focus on the targeted
sequencing of the human genome - one of the fastest-growing
segments of the $1 billion DNA sequencing market. This application
will enable the high-resolution analysis of genetic variation
between individuals and populations at a level unmatched by current
methodology.
For more information, please visit www.raindancetech.com.
RainStorm™ is a trademark of RainDance Technologies Inc.
About TGen
The Translational Genomics Research Institute (TGen) is a
nonprofit organization dedicated to conducting groundbreaking
research with life changing results. Research at TGen is focused on
helping patients with diseases such as cancer, neurological
disorders and diabetes. TGen is on the cutting edge of
translational research where investigators are able to unravel the
genetic components of common and complex diseases. Working with
collaborators in the scientific and medical communities, TGen
believes it can make a substantial contribution to the efficiency
and effectiveness of the translational process. For more
information, visit www.tgen.org.
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Notes to Editors:
Press inquiries: Don Goncalves, 781-793-9380,
[email protected]
Corporate questions: Steve Becker, 781-861-6300,
[email protected]
Technical questions: Jim Brayer, 781-861-6300,
[email protected]
TGen press contact: Steve Yozwiak, 602-343-8704,
[email protected]
In Europe: Patrick Kelly, +44-786-3200-242,
[email protected]
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