Dr. Liang is Director of the Collaborative Sequencing Center (CSC), Associate Professor in the Integrated Cancer Genomics and Neurogenomics Divisions, and Director of Scientific Operations at TGen. In 2010, Dr. Liang led the creation of the CSC, which acts as TGen’s primary next-generation sequencing resource. The center performs library construction and next-generation sequencing of whole genomes, exomes, ChIP DNA, and RNA on the Illumina platform, and has an emphasis on collaborative projects. Since its inception, the CSC has completed over 600 projects and has generated over 280Tb of raw sequencing data for studies encompassing a wide spectrum of diseases including DIPG (diffuse intrinsic pontine glioma), pancreatic cancer, cholangiocarcinoma, cutaneous and acral melanomas, Sézary syndrome, breast cancer, Alzheimer’s disease, diffuse large B-cell lymphoma, and breast cancer. The CSC has been involved in numerous studies including the longitudinal Multiple Myeloma Research Foundation (MMRF) study, the SU2C Genomics-Enabled Medicine for Melanoma trial, and clinical sequencing studies.
Dr. Liang’s research areas include cell-specific transcriptomics in Alzheimer’s disease, cancer genomics, and evaluating phenotypic variability in tuberous sclerosis, as well as precision medicine studies in DIPG and other cancers. Ms. Liang received her Bachelor of Science in Biological Sciences (Computational Biology Option) from Carnegie Mellon University, and her Ph.D. from Arizona State University in Molecular and Cellular Biology.