Sarah K. Highlander
Sarah K. Highlander

Sarah K. Highlander Ph.D.

Research Professor
Pathogen and Microbiome Division

Director, Microbiome Service Core
Pathogen and Microbiome Division

Sarah K. Highlander Ph.D.

Sarah Highlander is the Director of the Clinical Microbiome Service Center and Research Professor in the Pathogen and Microbiome Division at TGen North. Her current activities are directed toward development of a high performance, best in class, facility to support all aspects of clinical, veterinary and environmental microbiome studies at TGen, City of Hope and with outside collaborators.

Prior to joining TGen, Sarah was a Professor at the J. Craig Venter Institute in La Jolla, California, where she led projects on travelers’ diarrhea, antimicrobial resistance in pediatric diarrhea and juvenile caries in a twin cohort. Before joining JCVI, she was an Associate Professor in the Department of Molecular Virology and Microbiology and the Human Genome Sequencing Center at Baylor College of Medicine (BCM) in Houston, Texas. She has over thirty years of experience in medical microbiology with specific expertise in microbial genetics, genomics and infectious disease. Over the past ten years Sarah has become an expert in the field of human microbiome research. At BCM, she was a Principal Investigator on the NIH funded Human Microbiome Project , where she was involved in development of early protocols for human sample processing and analysis, including development of standards that are now widely used as controls for microbiome sample processing and sequencing.

Sarah received her undergraduate degree from the University of Michigan and M.S. and Ph.D. degrees in Medical Microbiology from the Sackler Institute of Biomedical Sciences at the New York University School of Medicine.

 

Host genetic control of the oral microbiome in health and disease Gomez A, Espinoza JL, Harkins DM, Leong P, Saffery R, Bockmann M, Torralba M, Kuelbs C, Kodukula R, Inman J, Hughes T, Craig JM, Highlander SK, Jones MB, Dupont CL, Nelson KE. Cell Host Microbe 2017 22:269-278

A robust ambient temperature collection and stabilization strategy: Enabling worldwide functional studies of the human microbiome Anderson EL, Li W, Klitgord N, Highlander SK, Dayrit M, Seguritan V, Yooseph S, Biggs W, Venter JC, Nelson KE, Jones MB. Sci Rep 2016 6:31731

Sequencing 16S rRNA gene fragments using the PacBio SMRT DNA sequencing system Schloss PD, Jenior ML, Koumpouras CC, Westcott SL, Highlander SK. PeerJ 2016 4:e1869

Library preparation methodology can influence genomic and functional predictions in human microbiome research Jones MB, Highlander SK, Anderson EL, Li W, Dayrit M, Klitgord N, Fabani MM, Seguritan V, Green J, Pride DT, Yooseph S, Biggs W, Nelson KE, Venter JC. Proc Natl Acad Sci USA 2015 112:14024-1029

Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence on the MiSeq Illumina sequencing pipeline  Kozich JJ, Westcott SL, Baxter NT, Highlander SK, Schloss PD. Appl Environ Microbiol 79:5112-5120

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