Genome Technology
The development and application of modern genome technology will be an essential component of TGen's objective of performing contemporary genetic analysis to benefit the health of the individual. Researchers in this area study the structure and function of genomes in normal and disease states, and have expertise in a wide range of genomic techniques.

Center for Computational Bioscience
The CCB engages in computational bioscience research and development collaborations with the TGen biomedical research programs; and provides computational resources, biomedical informatics support, and knowledge based data management systems to the TGen scientific staff. CCB conducts its research and development program with its four principal missions:

a. To develop and apply biostatistics, pattern recognition, data mining, text mining, and data visualization techniques to complex biomedical and clinical research problems

b. To develop and provide knowledge-based data management systems for the discovery of biomedical knowledge, including clinical informatics and management systems to develop and provide high performance computational methods and algorithms to analyze large volumes of scientific data and to simulate complex biological systems

c. To provide high performance computing resources and scientific research tools, including special-purpose parallel computing machines and high-density storage systems

d. To collaborate with the TGen scientific staff and colleagues at other research centers in applying state-of-art information technology to biomedical research problems

DNA Microarray Technology
Although all of the cells in the human body contain identical genetic material, the same genes are not active in every cell. Studying which genes are active and which are inactive in different cell types helps scientists to understand both how these cells function normally and how they are affected when various genes do not perform properly. In the past, scientists have only been able to conduct these genetic analyses on a few genes at once. With the development of DNA microarray technology, however, scientists can now examine how active thousands of genes are at any given time.